A Functional Assay for Sick Sinus Syndrome Genetic Variants
نویسندگان
چکیده
منابع مشابه
A Functional Assay for Sick Sinus Syndrome Genetic Variants.
BACKGROUND/AIMS Congenital Sick Sinus Syndrome (SSS) is a disorder associated with sudden cardiac death due to severe bradycardia and prolonged pauses. Mutations in HCN4, the gene encoding inward Na+/K+ current (If), have been described as a cause of congenital SSS. The objective of this study is to develop an SSS model in embryonic zebrafish, and use zebrafish as a moderate-throughput assay to...
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autoradiographic approach to Xenoh/CT LCBF measurements" at a time when most CT scanners were slow 20 seconds scan time) and interscan delays were much longer O 30 sec) than those currently available on many machines. There is no doubt that this method is now outdated. Since 1979—80 we, along with other groups, have been devel oping and using more sophisticated multivariable methods of analysi...
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ژورنال
عنوان ژورنال: Cellular Physiology and Biochemistry
سال: 2017
ISSN: 1015-8987,1421-9778
DOI: 10.1159/000479897